It is not known whether phenylephrine and promethazine passes into breast milk. Do not take phenylephrine and promethazine without first talking to your doctor if you are breast-feeding a baby. Inform patients that this drug may cause drowsiness, and they should avoid driving or operating machinery until the full effects of the drug are seen. Promethazine is an H1 receptor blocking agent. Read the Patient Information Leaflet if available from your pharmacist before you start taking promethazine and each time you get a refill. If you have any questions, ask your doctor or pharmacist. It may also be used for a short time to treat a runny nose due to the common cold. generic clozaril reacoes clozaril
Do not take phenylephrine and promethazine if you have taken a monoamine oxidase inhibitor MAOI such as isocarboxazid Marplan phenelzine Nardil tranylcypromine Parnate or selegiline Eldepryl in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects. The Supreme Court upheld the lower courts' rulings, stating that "Wyeth could have unilaterally added a stronger warning about IV-push administration" without acting in opposition to federal law. In effect, this means drug manufacturers can be held liable for injuries if warnings of potential adverse effects, approved by the FDA are deemed insufficient by state courts.
Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Preoperative, postoperative, or obstetric sedation. Side Effects List Promethazine HCL side effects by likelihood and severity.
Take this vitamin by with or without food, usually once daily. Follow all directions on the product package, or take as directed by your doctor. This is not a complete list of possible side effects. If you notice other side effects not listed above, contact your doctor or pharmacist. Don't watch TV or read. Put a cold pack or cool cloth on the painful area. Rest in a quiet, dark room.
Patients should be advised to avoid prolonged sun exposure during treatment. Keep track of how much of this medicine has been used. In the event that a patient complains of pain during intravenous injection of PHENERGAN Injection, the injection should be stopped immediately to evaluate for possible arterial injection or perivascular extravasation. Phenergan Promethazine HCl Suppositories are contraindicated in comatose states, and in individuals known to be hypersensitive or to have had an idiosyncratic reaction to promethazine or to other phenothiazines. Paxil paroxetine hydrochloride US prescribing information. Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. Atropine-like signs and symptoms-dry mouth, fixed, dilated pupils, flushing, as well as gastrointestinal symptoms-may occur. Rare Disease Database under "Rare Disease Information". Excessively large dosages of antihistamines, including Phenergan Promethazine HCl Suppositories, in pediatric patients may cause sudden death see OVERDOSAGE. Hallucinations and convulsions have occurred with therapeutic doses and overdoses of promethazine HCl in pediatric patients. In pediatric patients who are acutely ill associated with dehydration, there is an increased susceptibility to dystonias with the use of promethazine HCl. Promethazine, a phenothiazine derivative, is structurally different from the phenothiazines, with similar but different effects. Take this by as directed by your doctor. If you are self-treating, follow all directions on the product package. This combination of medicine may cause life-threatening effects to your heart. It is possible that the main title of the report is not the name you expected. Please check the listing to find the alternate names and covered by this report. Low blood sugar, or low glucose levels, causes shakiness, anxiety, clammy skin, irritability, hunger, and more. What should I discuss with my healthcare provider before taking phenylephrine and promethazine Phenergan Vc? Callan JE, Kostic MA, Bachrach EA, Rieg TS Oct 2008. "Prochlorperazine vs. promethazine for headache treatment in the emergency department: a randomized controlled trial". J Emerg Med.
Check the labels of all your medications to make sure you are not taking more than one product containing dextromethorphan. Inc. Baltimore, MD 21244. Drowsiness and confusion can increase the risk of falling. Phenergan Injection should not be given by the subcutaneous route because evidence of chemical irritation has been noted, and necrotic lesions have resulted following subcutaneous injection. The preferred parenteral route of administration is by deep intramuscular injection. When administered intravenously, Phenergan Injection should be given in a concentration no greater than 25 mg per mL and at a rate not to exceed 25 mg per minute. It is preferable to inject through the tubing of an intravenous infusion set that is known to be functioning satisfactorily. Phenergan Injection is contraindicated for use in pediatric patients less than 2 years of age see . Caution should be exercised when administering promethazine hydrochloride to pediatric patients 2 years of age or older. Solid promethazine is a white to faint-yellow, practically odorless, crystalline powder. Slow oxidation may occur upon prolonged exposure to air, usually causing blue discoloration. Its hydrochloride salt is freely soluble in water and somewhat soluble in alcohol. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist. cefixime
If these medicines don't work, your doctor can prescribe stronger medicine to stop the migraine. Oral formulations are preferred; however, rectal or parenteral formulations may be given if oral formulations are not tolerated. Asthma, nasal stuffiness, respiratory depression potentially fatal and apnea potentially fatal. Codeine is secreted into human milk. Administration of promethazine has been associated with reported cholestatic jaundice. Stimulation may be evident, especially in pediatric patients and geriatric patients. Convulsions may rarely occur. A paradoxical-type reaction has been reported in pediatric patients receiving single doses of 75 mg to 125 mg orally, characterized by hyperexcitability and nightmares. Elderly patients, particularly women, are most susceptible. Also, propylpiperazine derivatives like fluphenazine, perphenazine, prochlorperazine, and trifluoperazine may be more likely to induce this syndrome. Both the risk of developing TD and the likelihood that it will become irreversible increase with the duration and total cumulative dose of phenothiazine therapy administered. However, patients may infrequently develop symptoms after relatively brief treatment periods at low dosages. If TD occurs during phenothiazine therapy, prompt withdrawal of the offending agent or at least a lowering of the dosage should be considered. TD symptoms usually become more severe after drug discontinuation or a dosage reduction, but may gradually improve over months to years. In patients with preexisting drug-induced TD, initiating or increasing the dosage of phenothiazine therapy may temporarily mask the symptoms of TD but may eventually worsen the condition. PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Phenergan while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while using Phenergan. HEDIS Measure: . In many countries including the US and UK promethazine is contraindicated in children less than two years of age, and strongly cautioned against in children between two and six, due to problems with respiratory depression and sleep apnea. It was a nightmare with her. Specific studies to test the action of the drug on parturition, lactation, and development of the animal neonate were not done, but a general preliminary study in rats indicated no effect on these parameters. Although antihistamines have been found to produce fetal mortality in rodents, the pharmacological effects of histamine in the rodent do not parallel those in man. There are no adequate and well-controlled studies of Phenergan Promethazine HCl Suppositories in pregnant women. Drink plenty of fluids while taking this medication. Fluids will help to break up and clear congestion.
It does appear to be clear that a defect in the receptors to dopamine dopamine D2 receptor antagonism is an important contributor to the cause of neuroleptic malignant syndrome. How and by whom her death was first noticed, what quantity of which drugs, administered in what fashion and by whom, how she ended up dead in that bed in that room, who did what? This medication may cause withdrawal reactions, especially if it has been used regularly for a long time more than a few weeks or in high doses. Phenylephrine and promethazine is in the FDA pregnancy category C. This means that it is not known whether phenylephrine and promethazine will be harmful to an unborn baby. Do not take phenylephrine and promethazine without first talking to your doctor if you are pregnant or could become pregnant during treatment. Allergic conjunctivitis due to inhalant allergens and foods. Stimulation may be evident, especially in children and geriatric patients. Convulsions may rarely occur. A paradoxical-type reaction has been reported in children receiving single doses of 75 mg to 125 mg orally, characterized by hyperexcitability and nightmares. Drowsiness is the most prominent CNS effect of this drug. Sedation, somnolence, blurred vision, dizziness, confusion, disorientation, and extrapyramidal symptoms such as oculogyric crisis, torticollis, and tongue protrusion; lassitude, tinnitus, incoordination, fatigue, euphoria, nervousness, diplopia, insomnia, tremors, convulsive seizures, excitation, catatonic-like states, hysteria. Hallucinations have also been reported. This medication can cause side effects that may impair your thinking or reactions. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. There is no proven successful management of unintentional intra-arterial injection or perivascular extravasation after it occurs. Sympathetic block and heparinization have been employed during the acute management of unintentional intra-arterial injection, because of the results of animal experiments with other known arteriolar irritants. Peripheral neuropathy is a nerve condition of the extremities causing numbness, tingling, and pain. Phenergan Injection may cause marked drowsiness or impair the mental or physical abilities required for the performance of potentially hazardous tasks, such as driving a vehicle or operating machinery. Pediatric patients should be supervised to avoid potential harm in bike riding or in other hazardous activities. Who should not take Phenergan Vial? GJ, Roden DM, Zareba W. Prevention of torsade de pointes in hospital settings: a scientific statement from the American Heart Association and the American College of Cardiology Foundation. Boyer EW, Shannon M. The serotonin syndrome. cheapest curacne buy online visa
Parenteral formulations of this drug may cause severe chemical irritation and tissue damage regardless of the route. Talk about conspiracy theories. Though very unlikely, abnormal drug-seeking behavior is possible with this medication. Do not increase your dose, take it more frequently, or take it for a longer time than prescribed. Properly stop the medication when so directed. Subcutaneous injection is contraindicated as it may result in tissue necrosis. Primary brain tumors are often benign but can cause seizures, ongoing headaches, or loss of coordination. Tablets: Protect from light. This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Avoid alcoholic beverages. Noctec was GIVEN to her. It is not known whether Phenergan Injection is excreted in human milk. Because many drugs are excreted in human milk, and because of the potential for serious adverse reactions in nursing infants from Phenergan Injection, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Children may also experience excitability rather than drowsiness. If you have any questions, ask your doctor or pharmacist. Signs and symptoms of overdosage with promethazine HCl range from mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, and unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes Babinski reflex. When given concomitantly with Phenergan Injection, the dose of barbiturates should be reduced by at least one-half, and the dose of narcotics should be reduced by one-quarter to one-half. Dosage must be individualized. Excessive amounts of Phenergan Injection relative to a narcotic may lead to restlessness and motor hyperactivity in the patient with pain; these symptoms usually disappear with adequate control of the pain. Discuss the risks and benefits with your doctor.
Patients should be told to report any involuntary muscle movements. Some MEDICINES MAY INTERACT with Phenergan suppositories. Pyridoxine can cause side effects when taken in large doses for a long time. Sedating drugs may cause confusion and over-sedation in the elderly; elderly patients generally should be started on low doses of Phenergan Promethazine HCl Suppositories and observed closely. Phenergan Promethazine HCl Suppositories should be used with caution in patients with bone-marrow depression. Leukopenia and agranulocytosis have been reported, usually when promethazine HCl has been used in association with other known marrow-toxic agents. ALL meds. My 1 client I worked with 4 the full 6 yrs was on Noctec. Eventually it did nothing for him. But that was the ONLY sleep drug they were on. FORGET the Phenobarbital! Be safe with medicines. Read and follow all instructions on the label. Drugs used in nausea and Vertigo - Vomiting of pregnancy". After about a week Mom was almost back to herself. Phenylephrine and promethazine is used to treat symptoms such as itching, runny nose; sneezing; and congestion due to allergies or the common cold. cheapest symbicort mail order visa
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Phenergan suppositories while you are pregnant. If you are or will be breast-feeding while you use Phenergan suppositories, check with your doctor. Discuss any possible risks to your baby. Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Store phenylephrine and promethazine at room temperature away from moisture and heat. Who was behind the assassination of JFK? Phenylephrine and promethazine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, sedatives used to treat insomnia pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine unless your doctor approves. This product relieves apprehension and induces a quiet sleep from which the patient can be easily aroused. If you are using this medication on a regular schedule and you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Since recurrences of NMS have been reported with phenothiazines, the reintroduction of promethazine HCl should be carefully considered. Antiemetics should not be used in vomiting of unknown etiology in pediatric patients. What was the connection between all of the above during the sixties and how could it possibly have any bearing now? PHENERGAN is contraindicated for use in pediatric patients less than two years of age. Benzodiazepines are prescription medications that cause drowsiness, dizziness, blurred vision, and more. Tell your doctor if your condition does not improve or if it worsens. Phenothiazines may cause hypotension including orthostatic hypotension reflex tachycardia, increased pulse rate, syncope, and dizziness, particularly after the first parenteral dose but rarely after the first oral dose. Low-potency agents such as chlorpromazine and thioridazine are more likely to induce these effects, which usually subside within the first couple of hours following administration. Tolerance to the hypotensive effects often develops after a few doses. Rarely, fatal cardiac arrest has occurred secondary to severe hypotension. Other reported adverse cardiovascular effects include edema, thrombosis, and ECG abnormalities such as PR and QT interval prolongation, diffuse T-wave flattening, and ST segment depression. Therapy with phenothiazines should be avoided or otherwise administered cautiously in patients with severe cardiovascular disease, pheochromocytoma, a predisposition to hypotension, or conditions that could be exacerbated by hypotension such as a history of myocardial infarction, angina, or ischemic stroke. Close monitoring of cardiovascular status, including ECG changes, is recommended at all dosages. If parenteral therapy is given, patients should be in a supine position during administration and for at least 30 to 60 minutes afterwards. Patients who experience orthostatic hypotension should be cautioned not to rise too abruptly. Occasionally, when severe, hypotension may require treatment with vasoconstrictive agents such as norepinephrine or phenylephrine. Epinephrine should not be used, however, since phenothiazines can reverse its vasopressor effects and cause a further lowering of blood pressure.
Take this medication by with or without food, usually every 4 to 6 hours as needed with a full glass of water 8 ounces or 240 milliliters or as directed by your doctor. This medication can be taken with food if upset occurs. Drink plenty of fluids when you use this medication unless otherwise directed by your doctor. Neuroleptic malignant syndrome NMS is a possibly fatal syndrome that can be caused by Phenergan suppositories. Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your doctor at once if you have any of these symptoms. Do not use a household spoon because you may not get the correct dose. It may also be used to help certain narcotic pain relievers such as meperidine work better. Antiemetics are not recommended for treatment of uncomplicated vomiting in pediatric patients, and their use should be limited to prolonged vomiting of known etiology. Do not drink alcohol or use medicines that may cause drowsiness eg, sleep aids, muscle relaxers while you are using Phenergan suppositories; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness. Phenothiazines are extensively metabolized by the liver and may accumulate in patients with hepatic impairment. In addition, the use of some phenothiazines has been associated with adverse hepatic effects including cholestatic jaundice and elevated liver enzymes, generally within the first few months of therapy. SEVERE TISSUE INJURY, INCLUDING GANGRENE: Parenteral formulations can cause severe chemical irritation and damage to tissues regardless of the route of administration. gynera
Retrieved July 9, 2016. Phenergan Injection can cause severe chemical irritation and damage to tissues regardless of the route of administration. Irritation and damage can result from perivascular extravasation, unintentional intra-arterial injection, and intraneuronal or perineuronal infiltration. Adverse reactions include burning, pain, erythema, swelling, sensory loss, palsies, paralysis, severe spasm of distal vessels, thrombophlebitis, venous thrombosis, phlebitis, abscesses, tissue necrosis, and gangrene. Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Limited experience with dialysis indicates that it is not helpful. Use this medicine only as recommended. An intracranial hematoma occurs after a head injury and causes headache, drowsiness, confusion, and more. Phenergan Injection should be used with caution in patients with bone-marrow depression. Leukopenia and agranulocytosis have been reported, usually when promethazine hydrochloride has been used in association with other known marrow-toxic agents. You probably will not need lab tests, but your doctor may order some if he or she thinks your symptoms are caused by another disease. Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist. When administered intravenously, PHENERGAN Injection should be given in a concentration no greater than 25 mg per mL and at a rate not to exceed 25 mg per minute. It is preferable to inject through the tubing of an intravenous infusion set that is known to be functioning satisfactorily. Drowsiness, dizziness, constipation, blurred vision, or dry mouth may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Prevention and control of nausea and vomiting associated with certain types of anesthesia and surgery. It is best to inject this medication deep into a muscle. It may also be given by injection slowly into a large vein by a health care professional. Do not inject this medication under the skin or into an artery. For nausea and vomiting, use this medication as directed by your doctor, usually every 4 hours as needed. If you have any questions about the proper use of this medication, ask your doctor or pharmacist. The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians. Wernicke's encephalopathy can cause confusion, lack of muscle coordination, and vision problems. FDA pregnancy category C. This medication may be harmful to an unborn baby.
The answers are all contained in a set of diaries, The Red Diaries. Cellulitis, a bacterial infection of the skin, causes red, tender skin that is usually swollen and warm. Therapy adjunctive to meperidine or other analgesics for control of postoperative pain. Take the missed dose as soon as you remember. As an adjunct to preoperative or postoperative medication, 25 to 50 mg of Phenergan Injection in adults may be combined with appropriately reduced doses of analgesics and atropine-like drugs as desired. Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; blurred vision; burning, pain, swelling, or blistering around the injection site; confusion; excessive sweating; fainting; fever, chills, or persistent sore throat; hallucinations; loss of coordination; mental or mood changes eg, agitation, delirium, exaggerated sense of well-being, excitability, hysteria, nervousness; ringing in the ears; seizures; severe of persistent dizziness; shortness of breath or trouble breathing; slow or fast heartbeat; tremor; trouble sleeping; uncontrolled muscle movements eg, arm or leg movements, twitching of the face or tongue, jerking or twisting; unusual bruising or bleeding; yellowing of the skin or eyes. Many people using this medication not have serious side effects. Than she mixed up everything. buy uroxatral toronto store
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Check the labels on all your medicines such as allergy or cough-and-cold products because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely. Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. What other drugs will affect phenylephrine and promethazine Phenergan Vc? bbat.info trazodone
Moderate. These medicines may cause some risk when taken together. Long-term animal studies have not been performed to assess the carcinogenic potential of promethazine, nor are there other animal or human data concerning carcinogenicity, mutagenicity, or impairment of fertility with this drug. Promethazine was nonmutagenic in the Salmonella test system of Ames. If you are using the chewable tablets, chew each tablet well and swallow. If you are using the dissolving strips, allow each strip to dissolve on the and then swallow, with or without water. Active and prophylactic treatment of motion sickness.
Children may be more sensitive to the side effects of this drug, especially slowed breathing see Warning section. This drug can often cause excitement in young children instead of drowsiness. Special care should be taken when using this medication in children who have lost a lot of fluid dehydration those who have a family history of sudden infant death syndrome SIDS and those who are hard to wake up from sleep. How bad is that. This drug should not be used to treat nausea and vomiting of unknown etiology. Hallucinations have also been reported. B6 in people who not get enough of the vitamin from their diets. military and pharmacy and linezolid
Caution should be exercised when administering Phenergan Injection to pediatric patients 2 years of age and older. It is recommended that the lowest effective dose of PHENERGAN Injection be used in pediatric patients 2 years of age and older. Avoid concomitant administration of other drugs with respiratory depressant effects because of an association with respiratory depression, and sometimes death, in pediatric patients. Tell your doctor or pharmacist if you are taking other products such as alcohol, antihistamines such as cetirizine, diphenhydramine drugs for sleep or anxiety such as alprazolam, diazepam, zolpidem muscle relaxants such as carisoprodol, cyclobenzaprine and other narcotic pain relievers such as codeine, hydrocodone.